Djehuty is the god who is said to have invented writing, the measuring of time, music, magic, art, medicine, mathematics and astronomy. As early as in late Predynastic times he was depicted on slate palettes as an ibis, the sign of the 15th Lower Egyptian nome, so he might have originated there. But already in the 1st Dynasty he appears as a squatting baboon (Papio Cynocephalus) on statues at Abydos. His main cult center was later Khemenu (Gr: Hermopolis, modern Ashmunein) in Middle Egypt, where he took over the role of the eight creator gods of the Ogdoad; Eternity (Heh-Hehet), Darkness (Kek/Keket), Water/Potentiality (Nun/Nunet) and Wind/Hiddenness (Amen/Amenet), and became a creator god himself.

Donation stela, Necho II offering to Wesir, Aset and Djehuty seated 4 on the ground, and six lines of text concerning donation for maintaining lamp for Djehuty 'bull in the great mansion in Djedu', placed in charge of Djedjehutefankh (Dd-dh.wtj-jw.f-anh). Door-opener of Djedu, son of Pedehor (P3-dj-h.rwp|1Khj), year 11 of Necho II, in Chicago IL, Oriental Institute Museum.